The distribution of chloroquine in man after fatal poisoning
Identifieur interne : 003C05 ( Main/Exploration ); précédent : 003C04; suivant : 003C06The distribution of chloroquine in man after fatal poisoning
Auteurs : Ann E. Robinson [Royaume-Uni] ; Arnold I. Coffer [Royaume-Uni] ; Francis E. Camps [Royaume-Uni]Source :
- Journal of Pharmacy and Pharmacology [ 0022-3573 ] ; 1970-09.
Descripteurs français
- KwdFr :
- Adulte, Analyse spectrale, Biochimie de l'encéphale, Chloroquine (analyse), Chloroquine (intoxication), Chloroquine (sang), Chloroquine (urine), Chromatographie en phase gazeuse, Chromatographie sur couche mince, Estomac (analyse), Femelle, Foie (analyse), Humains, Myocarde (analyse), Poumon (analyse), Rein (analyse).
- MESH :
- analyse : Chloroquine, Estomac, Foie, Myocarde, Poumon, Rein.
- intoxication : Chloroquine.
- sang : Chloroquine.
- urine : Chloroquine.
- Adulte, Analyse spectrale, Biochimie de l'encéphale, Chromatographie en phase gazeuse, Chromatographie sur couche mince, Femelle, Humains.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Chloroquine.
- chemical , blood : Chloroquine.
- chemical , poisoning : Chloroquine.
- chemical , urine : Chloroquine.
- analysis : Kidney, Liver, Lung, Myocardium, Stomach.
- Adult, Brain Chemistry, Chromatography, Gas, Chromatography, Thin Layer, Female, Humans, Spectrum Analysis.
Abstract
Detailed analysis of autopsy specimens from two fatal cases of chloroquine poisoning is reported. Post‐mortem blood levels of 1.60 and 1.24 mg chloroquine/100 ml blood were found; results for liver blood, urine, stomach contents, liver, lungs and kidneys are given. The highest chloroquine concentration was in liver and the presence of a metabolite was demonstrated in the tissues.
Url:
DOI: 10.1111/j.2042-7158.1970.tb12756.x
Affiliations:
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Le document en format XML
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<term>Chloroquine (blood)</term>
<term>Chloroquine (poisoning)</term>
<term>Chloroquine (urine)</term>
<term>Chromatography, Gas</term>
<term>Chromatography, Thin Layer</term>
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<term>Humans</term>
<term>Kidney (analysis)</term>
<term>Liver (analysis)</term>
<term>Lung (analysis)</term>
<term>Myocardium (analysis)</term>
<term>Spectrum Analysis</term>
<term>Stomach (analysis)</term>
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<term>Chloroquine (analyse)</term>
<term>Chloroquine (intoxication)</term>
<term>Chloroquine (sang)</term>
<term>Chloroquine (urine)</term>
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<term>Foie (analyse)</term>
<term>Humains</term>
<term>Myocarde (analyse)</term>
<term>Poumon (analyse)</term>
<term>Rein (analyse)</term>
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<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Chloroquine</term>
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<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Chloroquine</term>
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<keywords scheme="MESH" type="chemical" qualifier="poisoning" xml:lang="en"><term>Chloroquine</term>
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<keywords scheme="MESH" type="chemical" qualifier="urine" xml:lang="en"><term>Chloroquine</term>
</keywords>
<keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Chloroquine</term>
<term>Estomac</term>
<term>Foie</term>
<term>Myocarde</term>
<term>Poumon</term>
<term>Rein</term>
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<term>Liver</term>
<term>Lung</term>
<term>Myocardium</term>
<term>Stomach</term>
</keywords>
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<term>Female</term>
<term>Humans</term>
<term>Spectrum Analysis</term>
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<term>Analyse spectrale</term>
<term>Biochimie de l'encéphale</term>
<term>Chromatographie en phase gazeuse</term>
<term>Chromatographie sur couche mince</term>
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<front><div type="abstract" xml:lang="en">Detailed analysis of autopsy specimens from two fatal cases of chloroquine poisoning is reported. Post‐mortem blood levels of 1.60 and 1.24 mg chloroquine/100 ml blood were found; results for liver blood, urine, stomach contents, liver, lungs and kidneys are given. The highest chloroquine concentration was in liver and the presence of a metabolite was demonstrated in the tissues.</div>
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<name sortKey="Coffer, Arnold I" sort="Coffer, Arnold I" uniqKey="Coffer A" first="Arnold I." last="Coffer">Arnold I. Coffer</name>
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